| Characters | Dictyosteliomycota | Acrasiomycota |
| Pseudopodia of amoebae | Filose | Lobose |
| Mitotic apparatus | Spindle pole bodies present | Spindle pole bodies absent |
| Pheromone | cAMP, others | Unknown |
| Migration of slug | Present | Absent |
| Prespore vacuoles | Present | Absent |
| Sorocarp differentiation | No germination of stalk cells | Germination of stalk cells |
| Spore and cyst walls | Cellulose | ? |
| Flagella | Absent | A few species reported to be biflagellate |
| Sexual reproduction | Macrocysts with meiosis | Not reported |